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- Bruker and Lawrence Berkeley National Laboratory Collaborate on Novel Technology for Structural...
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- MR Newsletter 08/2011
Pharmaceuticals
Magnetic resonance techniques have always played an important role in pharmaceutical research and across the pharmaceutical manufacturing industry. Throughout the entire process spectroscopic techniques based on magnetic resonance are used. Whether it is to identify new compounds, observe the interaction of drugs with a target protein, study the toxicology of drug candidates or identify properties of the final product, NMR, EPR and MRI provides the researcher with invaluable information.
Quantitative NMR in Drug Discovery
In Drug discovery, the majority of expensive, false positive screening results originate from erroneous assumptions on the concentrations of screening compounds. NMR has been proven to be superior to other typical methods used for concentration determination.
Nuclear magnetic resonance is a major tool for pharmaceutical drug discovery
Impurities and adulterants in starting materials pose potential health threats when present in the manufacturing of pharmaceutical APIs and drug products. These same impurities and adulterants may also result in lower production yields and greater needs for product purification. Screening starting materials using Assure™ - Raw Material Screening identifies problem samples prior to use and prevents costly manufacturing mistakes.
